Flagyl 500– Basic Info About This Antibiotic

Flagyl 500 is a broad-spectrum antimicrobial drug. It contains metronidazole, a substance of the nitro-5-imidazole group. Metronidazole is active against such strains asBifidobacterium, Bacteroidesfragilis, Bilophilia, Clostridium perfringens, Clostridium difficile, Eubacterium, Peptostreptococcus, Fusobacterium, Prophyromonas, Prevotella and Veilonella. The drug also slows down the development of protozoa strains, including Trichomonas vaginalis, Entamoebahistolytica, Giardia intestinalis (Lambliaintestinalis).

However, despite its high efficiency relatively the strains listed above, such strains as Actinomyces, Propionibacterium acnes and Mobilincus are insensitive to its action.

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Flagyl 500: Indications For The Intake

Flagylbelongs to prescription drugs. Buy Flagylin the following cases:

• protozoainfections including: trichomoniasis, giardiasis, amoebiasis, amoebic liver abscess;
• infections caused by anaerobic bacteria:peritonitis, abscesses of the abdomen and liver, endometritis, abscesses of the ovaries and fallopian tubes, postoperative complications, pneumonia, pleural empyema, lung abscess, meningitis, brain abscess, skin infections, bone infections, sepsis, endocarditis, yeast infection;
• prevention of complications during surgery: on the colon, appendectomy, gynecological surgeries;
• mixed aerobic and anaerobic bacterial infections;
• eradication of Helicobacter pylori in Helicobacter-associated gastric and duodenal ulcers, as part of complex therapy.

Flagyl is sometimes prescribed as one of the antibiotics as part of complex therapy for the eradication of Helicobacter pylori. It is not effective in the eradication of Helicobacter pylori outside of special regimens, without drugs that reduce the acidity of the stomach. It is also not used in any form for the treatment of gastric ulcer and duodenal ulcer and gastritis in the absence of Helicobacter pylori in the patient.

If one of the sexual partners is undergoing treatment, the other partner is also advised to take Flagyl, even if they have no symptoms of the disease. The fact is that they can be a carrier, and in this case, re-infection is possible.
Flagyl 500 does not work with viral infections, for example, common cold, flu, and so on.

How To Take Flagyl 500?

Flagyl tablets can come in 250 mg and 500 mg. Depending on the diagnosis, weight, and age of the patient, the doctor may prescribe different dosages of the drug. Usually, it is from 500 to 1500 mg per day. It is taken orally without chewing during or after meals. The main ingredient of Flagyl, metronidazole, is rapidly and almost completely absorbed (approximately 80% in 1 hour). After oral intake of 500 mg of metronidazole, the plasma concentration is 10 μg/ml in one hour, and 13.5 μg/ml in three hours. The half-life is 8-10 hours.

Do not exceed the recommended dose in order not to have vomiting, headache and flushing.

Contraindications for Flagyl 500

Flagyl is a safe drug. However, it still has some contraindications for use. Among them:

• organic lesions of the central nervous system (including epilepsy);
• impaired coordination of movements;
• blood diseases (including leukopenia);
• hepatic impairment (in the case of the appointment of large doses);
• Crohn disease;
• pregnancy;
• breastfeeding;
• hypersensitivity to imidazoles, as well as to nitroimidazole derivatives;
• children under 6.

Most Common Side Effects

As we have already said, Flagyl is a fairly safe drug and patients feelgood during the treatment. But, in some cases, the following adverse effectsare possible:

• From the gastrointestinal tract: nausea, metallic taste in the mouth, dry mouth, loss of appetite, glossitis, stomatitis, pancreatitis, anorexia, epigastric pain, vomiting, diarrhea, constipation, abdominal cramping.
• From the nervous system: headache, dizziness, impaired coordination of movements, ataxia, confusion, irritability, depression, weakness, insomnia, convulsions, confusion, hallucinations, peripheral neuropathy (especially with prolonged use).
• Allergic reactions: urticaria, skin rash, skin flushing, nasal congestion, fever, arthralgia.
• From the urinary system: dysuria, polyuria, cystitis, urinary incontinence, candidiasis, urine staining is possible in a brownish-reddish color.
• Others: neutropenia, leukopenia, flattening of the T wave on the ECG.
• Local reactions (when using vaginal suppositories): a burning sensation or irritation of the penis in a sexual partner, a burning sensation or increased urination, vulvitis (itching, burning pain or hyperemia of the mucous membrane in the external genital area).

Conduct your doctor if any of the symptoms above continue for more than 3 days. Stop taking metronidazole if cramps, nausea, vomiting, headache do not pass away after the 5th day.

Drug Interactions

Patients should not take Flagyl in parallel with consuming alcoholic beverages. Otherwise, all sorts of unpleasant sensations are possible. In this case, side effects can include nausea, vomiting, etc.

Before you start treatment with Flagyl, inform your doctor about all medicines you take, including prescription drugs and organic remedies.

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